BACKGROUND Blood glucose (BG) is a risk factor of adverse prognosis in non-diabetic patients in several conditions. However, a limited number of studies were performed to explore the relationship between postoperative BG and adverse outcomes in non-diabetic patients with rheumatic heart disease (RHD). METHODS We identified 1395 non-diabetic patients who diagnosed with having RHD, and underwent at least one valve replacement and preoperative coronary angiography. BG was measured at admission to the intensive care unit (ICU) after surgery. The association of postoperative BG level with in-hospital and one-year mortality was accordingly analyzed. RESULTS Included patients were stratified into four groups according to postoperative BG level's (mmol/L) quartiles: Q1 (< 9.3 mmol/L, n = 348), Q2 (9.3-10.9 mmol/L, n = 354), Q3 (10.9-13.2 mmol/L, n = 341), and Q4 (≥ 13.2 mmol/L, n = 352). The in-hospital death (1.1% vs. 2.3% vs. 1.8% vs. 8.2%, P < 0.001) and MACEs (2.0% vs. 3.1% vs. 2.6% vs. 9.7%, P < 0.001) were significantly higher in the upper quartiles. Postoperative BG > 13.0 mmol/L was the best threshold for predicting in-hospital death (area under the curve (AUC) = 0.707, 95% confidence interval (CI): 0.634-0.780, P < 0.001). Multivariate logistic regression analysis indicated that postoperative BG > 13.0 mmol/L was an independent predictor of in-hospital mortality (adjusted odds ratio (OR) = 3.418, 95% CI: 1.713-6.821, P < 0.001). In addition, Kaplan-Meier curve analysis showed that the risk of one-year death was increased for a postoperative BG > 13.2 (log-rank = 32.762, P < 0.001). CONCLUSION Postoperative BG, as a routine test, could be served as a risk measure for non-diabetic patients with RHD.

中文翻译：

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非糖尿病风湿性心脏病患者术后血糖的预后价值。

背景技术血糖（BG）是在几种情况下非糖尿病患者不良预后的危险因素。然而，进行了有限数量的研究以探讨风湿性心脏病（RHD）的非糖尿病患者术后BG与不良预后之间的关系。方法我们确定了1395例诊断为RHD的非糖尿病患者，并至少进行了一次瓣膜置换和术前冠状动脉造影。手术后进入重症监护室（ICU）时测量BG。相应地分析了术后BG水平与院内死亡率和一年死亡率的关系。结果根据术后BG水平（mmol / L）四分位数将患者分为四组：Q1（<9.3 mmol / L，n = 348），Q2（9.3-10.9 mmol / L，n = 354），Q3（10.9） -13.2 mmol / L，n = 341）和Q4（≥13.2 mmol / L，n = 352）。院内死亡率（1.1％vs. 2.3％vs. 1.8％vs. 8.2％，P <0.001）和MACEs（2.0％vs. 3.1％vs. 2.6％vs. 9.7％，P <0.001）显着更高在上四分位数中。术后BG> 13.0 mmol / L是预测院内死亡的最佳阈值（曲线下面积（AUC）= 0.707，95％置信区间（CI）：0.634-0.780，P <0.001）。多元logistic回归分析表明，术后BG> 13.0 mmol / L是院内死亡率的独立预测因子（校正比值比（OR）= 3.418，95％CI：1.713-6.821，P <0.001）。此外，Kaplan-Meier曲线分析显示，术后BG> 13.2时，一年死亡的风险增加（log-rank = 32.762，P <0.001）。结论术后BG作为常规检查，