Endometriosis, a condition in which uterine tissue grows outside the uterus, is a debilitating disease, affecting millions of women and costing the United States approximately $78 billion annually in pain- related disability. It is also the leading cause of chronic pelvic pain (CPP), which is often unresponsive to existing treatments. Adolescent women with the disease are at particular risk as there are often significant diagnostic delays, which in turn can exacerbate pain. Research and treatment guidelines for adolescents with endometriosis are largely based on studies for adult women due to the limited number of studies focusing on adolescents. The current paper critically reviews the literature as it pertains to endometriosis pathophysiology, mechanisms contributing to CPP, and treatment implications and recommendations with a focus on gaps related to adolescents.

中文翻译：

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青少年子宫内膜异位症和疼痛 - 早期打击以限制痛苦：叙述性评论。

子宫内膜异位症是一种子宫组织在子宫外生长的疾病，是一种使人衰弱的疾病，影响着数百万妇女，每年因疼痛相关的残疾给美国造成约 780 亿美元的损失。它也是慢性盆腔疼痛 (CPP) 的主要原因，慢性盆腔疼痛通常对现有治疗无反应。患有这种疾病的青春期女性面临的风险特别高，因为通常会出现严重的诊断延误，这反过来又会加剧疼痛。由于针对青少年的研究数量有限，针对患有子宫内膜异位症的青少年的研究和治疗指南主要基于对成年女性的研究。目前的论文批判性地回顾了与子宫内膜异位症病理生理学、促成 CPP 的机制有关的文献，