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Chemoprotective and antiobesity effects of tocols from seed oil of Maqui-berry: Their antioxidative and digestive enzyme inhibition potential.
Food and Chemical Toxicology ( IF 4.3 ) Pub Date : 2019-12-17 , DOI: 10.1016/j.fct.2019.111036
José Miguel Bastías-Montes 1 , Karen Monterrosa 1 , Ociel Muñoz-Fariña 2 , Olga García 2 , Sergio M Acuña-Nelson 1 , Carla Vidal-San Martín 1 , Roberto Quevedo-Leon 3 , Isao Kubo 4 , Jose G Avila-Acevedo 5 , Mariana Domiguez-Lopez 6 , Zhao-Jun Wei 7 , Kiran Thakur 7 , Carlos L Cespedes-Acuña 8
Affiliation  

Maqui-berry (Aristotelia chilensis) is the emerging Chilean superfruit with high nutraceutical value. Until now, the research on this commodity was focused on the formulations enriched with polyphenols from the pulp. Herein, contents of tocols were compared in the seed oil of Maqui-berry obtained through three different extraction methods followed by determining their antioxidative and enzyme inhibitions in-vitro. Firstly, oilseed was extracted with n-hexane (Soxhlet method), chloroform/methanol/water (Bligh and Dyer method) and pressing (industrial). These samples were used to access their effects against DPPH, HORAC, ORAC, FRAP, Lipid-peroxidation (TBARS), α-amylase, α-glucosidase, and pancreatic lipase. All the isomers of tocopherol and tocotrienol were identified, and β-sitosterol was the only sterol found in higher amounts than other vegetable oils. The Bligh and Dyer method could lead to the highest antioxidative capacity compared to Soxhlet and press methods likely because the latter have a higher amount of tocopherols. Further, seed oil from Maqui berry and their tocols (α, β, γ, δ-tocopherols, tocotrienols, and β-sitosterol) warrant clinical investigation for their antioxidative and antiobesity potential. Taken together, these findings provide relevant and suitable conditions for the industrial processing of Maqui-berry.

中文翻译:

Maqui-berry种子油中母育酚的化学保护和抗肥胖作用:它们的抗氧化和消化酶抑制潜能。

Maqui-berry(Aristotelia chilensis)是新兴的智利超级水果,具有很高的营养价值。迄今为止,对该商品的研究一直集中在富含纸浆中多酚的配方上。在本文中,比较了通过三种不同提取方法获得的马基莓种子油中母育酚的含量,然后体外测定了其抗氧化和酶抑制作用。首先,用正己烷(Soxhlet法),氯仿/甲醇/水(Bligh和Dyer法)萃取油籽并压榨(工业用)。这些样品用于获得其对DPPH,HORAC,ORAC,FRAP,脂质过氧化(TBARS),α-淀粉酶,α-葡萄糖苷酶和胰腺脂肪酶的作用。鉴定了生育酚和生育三烯酚的所有异构体,β-谷甾醇是唯一含量高于其他植物油的甾醇。与索氏提取法和压榨法相比,Bligh和Dyer方法可能导致最高的抗氧化能力,这可能是因为后者的生育酚含量更高。此外,来自马基浆果的种子油及其母育酚(α,β,γ,δ-生育酚,生育三烯酚和β-谷甾醇)具有抗氧化和抗肥胖的潜力,因此值得临床研究。综上所述,这些发现为马基浆果的工业加工提供了相关且合适的条件。和β-谷固醇)的抗氧化和抗肥胖潜力值得临床研究。综上所述,这些发现为马基浆果的工业加工提供了相关且合适的条件。和β-谷固醇)的抗氧化和抗肥胖潜力值得临床研究。综上所述,这些发现为马基浆果的工业加工提供了相关且合适的条件。
更新日期:2019-12-18
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