STUDY DESIGN Health-related quality of life (HRQOL) data from two parallel independent single-blinded controlled randomized studies of manual (Study 1) and robotic (Study 2) locomotor training were combined (ClinicalTrials.gov #NCT00854555). OBJECTIVE To assess effects of body-weight supported locomotor training (BWSLT) programs on HRQOL in persons with long-standing motor incomplete spinal cord injury and poor walking function. SETTINGS Two inpatient rehabilitation facilities and one outpatient clinic in Norway. METHODS Data were merged into intervention (locomotor training 60 days) or control group ("usual care"). Participants completed questionnaires before randomization and 2-4 weeks after the study period, including demographic characteristics, HRQOL (36-Item Short-Form Health Status Survey, SF-36), physical activity (The International Physical Activity Questionnaire Short Form, IPAQ-SF), exercise barrier self-efficacy (EBSE), and motivation for training (Behavioral Regulation in Exercise Questionnaire, BREQ). Physical outcomes i.e., Lower extremity motor score (LEMS) was assessed. The main outcome was change in HRQOL. Secondary outcomes included changes in IPAQ-SF, EBSE, BREQ, and physical outcomes. RESULTS We recruited 37 of 60 predetermined participants. They were autonomously motivated with high baseline physical activity. BWSLT with manual or robot assistance did not improve HRQOL, though LEMS increased in the BWSLT group compared with control group. CONCLUSIONS The study was underpowered due to recruitment problems. The training programs seem to benefit LEMS, but not other physical outcomes, and had minimal effects on HRQOL, EBSE, and motivation. Autonomous motivation and high physical activity prior to the study possibly limited the attainable outcome benefits, in addition to limitations due to poor baseline physical function.

中文翻译：

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在长期不完全病变的脊髓损伤患者中，体重支持的运动训练的生活质量和心理结果。

研究设计将来自两项并行的独立（手动）（研究1）和机器人（研究2）运动训练的随机单盲对照随机研究的健康相关生活质量（HRQOL）数据（ClinicalTrials.gov＃NCT00854555）。目的评估体重支持的运动训练（BWSLT）程序对长期运动不完全性脊髓损伤和步行功能差的人的HRQOL的影响。地点挪威有两个住院康复设施和一个门诊诊所。方法将数据合并为干预（运动训练60天）或对照组（“常规护理”）。参加者在随机分组之前和研究期后的2-4周完成问卷调查，包括人口统计学特征，HRQOL（36项简短健康状况调查，SF-36），身体活动（国际身体活动问卷简称，IPAQ-SF），运动障碍自我效能感（EBSE）和锻炼动机（运动问卷中的行为规范，BREQ）。评估身体结局，即下肢运动评分（LEMS）。主要结果是HRQOL的改变。次要结果包括IPAQ-SF，EBSE，BREQ和身体结果的变化。结果我们招募了60名预定参与者中的37名。他们具有较高的基线体育活动自主动机。尽管与对照组相比，BWSLT组的LEMS有所增加，但使用人工或机器人辅助的BWSLT并未改善HRQOL。结论由于招聘问题，该研究的动力不足。培训计划似乎使LEMS受益，但对其他身体结局却无济于事，并且对HRQOL，EBSE，和动机。在研究之前的自主动机和较高的体育活动可能会限制可获得的结果益处，此外还会因基线身体机能较差而造成限制。