This report describes the synthesis of magnetic [email protected] (i.e., NiFe core with Au shell) nanoparticles as functional spectroscopic probes. Both of the magnetic NiFe nanoparticles and its composite [email protected] particles were synthesized in aqueous solution. It is more analogous with the biological organism environment. The composite nanoparticles were dispersible in aqueous solution and could be directed by a magnetic field. Such [email protected] nanoparticles have been shown to function as magnetic and spectroscopic nanoprobes for surface enhanced Raman scattering (SERS) detection of molecules attached to the surface of the nanoparticles. It shows more potential functional SERS nanoprobes for biomolecular separation and detection.

该报告描述了磁性[电子邮件保护的]（即具有Au壳的NiFe核）纳米粒子的合成，作为功能性光谱探针。磁性NiFe纳米颗粒及其复合材料（受电子邮件保护的）颗粒都是在水溶液中合成的。它更类似于生物有机体环境。复合纳米颗粒可分散在水溶液中，并可以通过磁场引导。此类[受电子邮件保护的]纳米粒子已显示出磁性和光谱纳米探针的功能，用于表面增强拉曼散射（SERS）检测附着在纳米粒子表面的分子。它显示了用于生物分子分离和检测的更多潜在功能性SERS纳米探针。