Intestinal mucous cells produce and secrete mucins which hydrate, lubricate and protect the intestinal epithelium from mechanical injuries due to the transition of digesta or action of pathogens. Intestinal mucous cells are considered elements of the innate immune system as they secrete lectins, toxins, immunoglobulins, and anti-microbial peptides. Acid mucins can surround and eliminate many pathogenic microorganisms. We performed a quantitative analysis of the density and mucus composition of different intestinal mucous cell types from mullet (Chelon ramada) that were infected solely with Neoechinorhynchus agilis. Most N. agilis were encountered in the middle region of the intestine. Mucous cell types were identified with Alcian Blue (pH2.5) and Periodic acid-Schiff (PAS) histochemistry, and by staining with a panel of seven lectins. Mucus enriched for high viscosity acid mucins was accumulated near points of worm attachment. Parasites were surrounded by an adherent mucus layer or blanket. Ultrastructural examination showed intestinal mucous cells typically possessed an elongated, basally positioned nucleus and numerous electron dense and lucent vesicles in the cytoplasm. The results show both an increase in mucus production and changes in mucin composition in infected mullet in comparison with uninfected conspecifics.

中文翻译：

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Chelon ramada肠黏膜细胞对肠道蠕虫Neoechinorhynchus agilis（Acanthocephala）的黏液分泌的差异性粘蛋白。

肠粘液细胞产生并分泌粘蛋白，这些粘蛋白可水合，润滑并保护肠上皮免受由于消化物转变或病原体作用而引起的机械损伤。肠道粘液细胞因分泌凝集素，毒素，免疫球蛋白和抗微生物肽而被认为是先天免疫系统的组成部分。酸性粘蛋白可以包围并消除许多病原微生物。我们对鱼（Chelon ramada）的不同肠道粘液细胞类型的密度和粘液成分进行了定量分析，这些cell鱼仅感染了新奇棘鱼。大多数的敏捷猪笼草都在肠道的中部遇到。粘液细胞类型通过Alcian Blue（pH2.5）和高碘酸Schiff（PAS）组织化学方法鉴定，并用7种凝集素染色。在蠕虫附着点附近聚集了富含高粘度酸性粘蛋白的粘液。寄生虫被粘附的粘液层或毯子包围。超微结构检查显示，肠粘液细胞通常在细胞质中具有细长的，基本定位的细胞核和大量电子密集且透明的囊泡。结果表明，与未感染的同种菌相比，被感染的鱼的粘液产生增加，粘蛋白组成发生变化。