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Back to the Future: Effector Fate during T Cell Exhaustion.
Immunity ( IF 25.5 ) Pub Date : 2019-12-17 , DOI: 10.1016/j.immuni.2019.11.007
Veit R Buchholz 1 , Dirk H Busch 2
Affiliation  

Exhausted CD8+ T cells adopt a functionally attenuated state but still confer a certain degree of pathogen control. Chen et al. (2019), Hudson et al. (2019), and Zander et al. (2019) assign the lasting maintenance of this restrained pathogen control to an equilibrium of effector-like, transitory, terminal, and memory-like exhausted T cells.

中文翻译:

回到未来:T细胞衰竭期间的效应子命运。

精疲力竭的CD8 + T细胞处于功能减弱状态,但仍可对病原体进行一定程度的控制。Chen等。(2019),Hudson等。(2019)和Zander等人。(2019)将这种受约束的病原体控制的持久维持分配给效应器样,短暂,终末和记忆样的T细胞平衡。
更新日期:2019-12-18
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