Functional genomics is at the core of studying the exact function of genes. However, homozygous knockouts of essential and pleiotropic effectors (almost 10% of the genome) are not always possible, thus, functions of these genes remain obscured. The tissue-specific genome editing tool (CRISPR-TSKO) recently described by Decaestecker et al., can characterize these indispensable genes and has wide applications in plants.

中文翻译：

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CRISPR-TSKO：一种用于植物中特定组织基因组编辑的工具。

功能基因组学是研究基因确切功能的核心。然而，必需和多效效应子（几乎占基因组的10％）的纯合敲除并非总是可能的，因此，这些基因的功能仍然被遮盖。Decaestecker等人最近描述的组织特异性基因组编辑工具（CRISPR-TSKO）。可以表征这些必不可少的基因，并在植物中具有广泛的应用。