A large number of trifluoromethylthiolation methods have been developed, but a trifluoromethylthiolation reagent usually has to be used in these methods. Herein we describe a difluorocarbene-based trifluoromethylthiolation of terminal alkynes to construct a Csp-SCF₃ bond catalysed by a copper complex. Ph₃P⁺CF₂CO₂-/S₈/F- was used as a reagent system to form the CF₃S- anion, and the sequential formation of CF₂=S, F-CF₂S and C-SCF₃ bonds was achieved in a one-step process.

中文翻译：

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末端炔烃的基于二氟卡宾的三氟甲基硫醇化

已经开发了大量的三氟甲基硫醇化方法，但是在这些方法中通常必须使用三氟甲基硫醇化试剂。在本文中，我们描述了末端炔烃的基于二氟卡宾的三氟甲基硫醇化，以构建由铜配合物催化的Csp-SCF ₃键。用Ph ₃ P ⁺ CF ₂ CO _2- / S ₈ / F-作为试剂体系形成CF ₃ S-阴离子，依次形成CF ₂ = S，F-CF ₂ S和C-SCF ₃一步一步就可以实现纽带。