Recent advances in the biosensing of neurotransmitters: material and method overviews towards the biomedical analysis of psychiatric disorders,Analytical Methods

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Recent advances in the biosensing of neurotransmitters: material and method overviews towards the biomedical analysis of psychiatric disorders
Analytical Methods ( IF 2.7 ) Pub Date : 2019/12/16 , DOI: 10.1039/c9ay02390a
Ahmad Mobed _{1,

2,

3,

4,

5} , Mohammad Hasanzadeh _{4,

5,

6,

7} , Ali Ahmadalipour _{1,

2,

3,

4,

5} , Ali Fakhari _{1,

2,

3,

4,

5}

Affiliation

Neurotransmitters are the most important messengers of the nervous system, and any changes in their balances and activities can cause serious neurological, psychiatric and cognitive disorders such as schizophrenia, Alzheimer's disease and Parkinson's disease. This review highlights the importance of biosensors as a powerful tool for the detection of neurotransmitters. The first part of this study is related to the introduction of neurotransmitters and their importance, and the routine methods in their identification are discussed later. The most attractive point in the present review is the integration of various biosensors in order to identify the neurotransmitters and assess their sensitivity and specificity more easily than the conventional methods. Also, the application of advanced nanomaterials in the biosensing of neurotransmitters is discussed. We hope that this study can be very striking and helpful for the research on the engineering of novel sensing biodevices for the detection of neurotransmitters in clinical samples.

中文翻译：

神经递质的生物传感的最新进展：精神疾病的生物医学分析的材料和方法概述

神经递质是神经系统最重要的使者，其平衡和活动的任何变化都可能导致严重的神经，精神病和认知障碍，例如精神分裂症，阿尔茨海默氏病和帕金森氏病。这篇评论强调了生物传感器作为检测神经递质的有力工具的重要性。本研究的第一部分与神经递质的引入及其重要性有关，稍后将讨论鉴定它们的常规方法。本综述中最吸引人的一点是各种生物传感器的集成，以便比传统方法更容易识别神经递质并评估其敏感性和特异性。还，讨论了先进的纳米材料在神经递质的生物传感中的应用。我们希望这项研究能够非常引人注目，并有助于研究用于检测临床样品中神经递质的新型传感生物装置的工程设计。

更新日期：2020-02-13

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