Three induced pluripotent stem cells (iPSC) clones NCCSi007-A, NCCSi007-B and NCCSi007-C were generated from CD4⁺T cells of a 38 years old male patient suffering from liver cirrhosis- alcoholic and minimal hepatic encephalopathy of Indian origin. The CD4⁺T cells of the patient were reprogrammed using integration free, Sendai viral vector system. Each of the three iPSC clones showed high alkaline phosphatase (ALP) activity, expressed pluripotency markers OCT4, SOX2, NANOG, KLF4, SSEA-4, TRA-1–60, showed normal male karyotype (46, XY) and exhibited multi-lineage differentiation.

中文翻译：

---

来自印度裔酒精性肝硬化患者的无整合诱导多能干细胞系的三个克隆（NCCSi007A，NCCSi007B和NCCSi007C）的生成和表征。

从一名来自印度肝性肝硬化，酒精性和最小型肝性脑病的38岁男性患者的CD4 ⁺ T细胞产生了三个诱导的多能干细胞（iPSC）克隆NCCSi007-A，NCCSi007-B和NCCSi007-C 。使用无整合的仙台病毒载体系统对患者的CD4 ⁺ T细胞进行重新编程。三个iPSC克隆中的每一个均显示高碱性磷酸酶（ALP）活性，表达多能性标记OCT4，SOX2，NANOG，KLF4，SSEA-4，TRA-1–60，显示正常的男性核型（46，XY）并显示多谱系差异化。