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Tailor-made GPCRs.
Nature Chemical Biology ( IF 12.9 ) Pub Date : 2020-01-01 , DOI: 10.1038/s41589-019-0427-y
R Scott Prosser 1
Affiliation  

An in silico directed evolution approach using first principles of allostery predicts the effects of protein sequence and structure variation on constitutive activity and ligand response in GPCRs.

中文翻译:

量身定制的GPCR。

使用变构第一原理的计算机定向进化方法可预测蛋白质序列和结构变异对GPCR中本构活性和配体反应的影响。
更新日期:2019-12-17
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