OBJECTIVES Although more than 1.8 million people survive snakebite envenomation each year, their recovery is understudied. Obtaining long-term follow-up is challenging in both high- and low-resource settings. The Patient-Specific Functional Scale (PSFS) is an easily administered, well-accepted patient-reported outcome that is validated for assessing limb recovery from snakebite envenomation. We studied whether the PSFS is valid and reliable when administered by telephone. METHODS This is a secondary analysis of data from a randomized clinical trial. We analyzed the results of PSFS collected in-person on days 3, 7, 14, 21, and 28 and by telephone on days 10, 17, and 24. We assessed the following scale psychometric properties: (a) content validity (ceiling and floor effects), (b) internal structure and consistency (Cronbach's alpha), and (c) temporal and external validity using Intraclass Correlation Coefficient (ICC). Temporal stability was assessed using Spearman's correlation coefficient and agreement between adjacent in-person and telephonic assessments with Cohen's kappa. Bland Altman analysis was used to assess differential bias in low and high score results. RESULTS Data from 74 patients were available for analysis. Floor effects were seen in the early post-injury time points (median: 3 (IQR: 0, 5) at 3 days post-enrollment) and ceiling effects in the late time points (median: 9 (IQR: 8, 10). Internal consistency was good to excellent with both in-person (Cronbach α: 0.91 (95%CI 0.88, 0.95)) and telephone administration (0.81 (0.73, 0.89). Temporal stability was also good (ICC: 0.83 (0.72, 0.89) in-person, 0.80 (0.68, 0.88) telephone). A strong linear correlation was found between in-person and telephone administration (Spearman's ρ: 0.83 (CI: 0.78, 0.84), consistency was assessed as excellent (Cohen's κ 0.81 (CI: 0.78, 0.84), and Bland Altman analysis showed no systematic bias. CONCLUSIONS Telephone administration of the PSFS provides valid, reliable, and consistent data for the assessment of recovery from snakebite envenomation.

中文翻译：

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电话评估患者特定功能量表的有效性和可靠性，以评估蛇咬毒液的恢复情况。

目标尽管每年有超过180万人幸免于蛇咬毒害，但对其康复的研究仍不足。在资源丰富和资源匮乏的环境中，进行长期随访都具有挑战性。特定于患者的功能量表（PSFS）是一种易于管理，广为接受的患者报告的结局，已验证可用于评估从蛇咬毒害中恢复肢体。我们研究了通过电话管理时PSFS是否有效和可靠。方法这是对来自随机临床试验的数据的二次分析。我们分析了在第3、7、14、21和28天亲自收集的PSFS的结果，并在第10、17和24天通过电话分析了PSFS的结果。我们评估了以下量表的心理计量学特性：（a）内容的有效性（上限和下限） （b）内部结构和一致性（克朗巴赫（Cronbach）的alpha），（c）使用类内相关系数（ICC）的时间和外部有效性。使用Spearman的相关系数以及Cohen的kappa在相邻的面对面和电话评估之间的一致性来评估时间稳定性。Bland Altman分析用于评估低分和高分结果中的差异偏倚。结果74例患者的数据可供分析。在受伤后的早期时间点（入组后3天的中位数：3（IQR：0，5））观察到地板效应，在后期的时间点（中位数：9（IQR：8、10））观察到天花板效应。面对面的（Cronbachα：0.91（95％CI 0.88，0.95））和电话管理的内部一致性（0.81（0.73，0.89））良好至优异。时间稳定性也很好（ICC：0.83（0.72，0.89）面对面的0.80（0.68、0.88）电话）。