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Recovery rate and determinants of severe acute malnutrition children treatment in Ethiopia: a systematic review and meta-analysis.
Systematic Reviews ( IF 3.7 ) Pub Date : 2019-12-13 , DOI: 10.1186/s13643-019-1249-4
Kassahun Gebeyehu Yazew 1 , Chanyalew Worku Kassahun 1 , Amare Wondim Ewnetie 1 , Habtamu Kerebih Mekonen 2 , Endalamaw Salilew Abagez 2
Affiliation  

BACKGROUND Severe acute malnutrition affects more than 20 million children. Africa is pointed out as a region where the problem is highly prevalent. There were individual studies on the recovery rate and its determinants among children with severe acute malnutrition in Ethiopia. But, there is no national pooled estimate. Therefore, this systematic review and meta-analysis aimed to estimate the recovery rate and determinants among children with severe acute malnutrition admitted to the therapeutic feeding unit in Ethiopia. METHODS The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline was followed in this study. Studies were accessed through electronic web-based search from PubMed, Cochrane Library, Google Scholar, and EMBASE. The statistical analysis was conducted using STATA version-11 software. The pooled prevalence was estimated with 95% confidence intervals using a random-effects model. RESULT A total of 12 studies were included with 2658 participants in the analysis. The overall pooled estimated recovery rate among children with severe acute malnutrition admitted to the inpatient therapeutic feeding unit in Ethiopia was 72.02 % (CI, 64.83, 79.22%). In the subgroup analysis, the highest estimate (80.29%) was observed in studies conducted in Oromia regional state, while 68.63% was observed in studies Southern Nation Nationality of people region 68.63%. Children who had no congestive heart failure were 4.88 times (OR, 4.88; 95% CI, 2.246, 10.586) more likely to recover than their counterparts. CONCLUSION The recovery rate among severe acute malnourished children on the therapeutic feeding unit in Ethiopia lied within the international minimum sphere. Hence, health care providers shall strengthen the management of severe acute malnutrition and management other co-morbidities like congestive heart failure. SYSTEMATIC REVIEW REGISTRATION PROSPERO CRD42019119124.

中文翻译:

埃塞俄比亚严重急性营养不良儿童治疗的恢复率和决定因素:系统评价和荟萃分析。

背景技术严重的急性营养不良影响着超过2000万儿童。指出非洲是这个问题高度普遍的地区。埃塞俄比亚有严重急性营养不良儿童的康复率及其决定因素的个别研究。但是,没有国家汇总估算。因此,这项系统的回顾和荟萃分析旨在评估埃塞俄比亚治疗性进食单位收治的严重急性营养不良儿童的康复率和决定因素。方法本研究遵循系统评价和荟萃分析指南的首选报告项目。通过PubMed,Cochrane Library,Google Scholar和EMBASE的基于Web的电子搜索来访问研究。使用STATA 11版软件进行统计分析。使用随机效应模型以95%的置信区间估计合并患病率。结果分析共纳入12项研究,共有2658名参与者。埃塞俄比亚住院治疗性进食单位收治的严重急性营养不良儿童的总体估计恢复率为72.02%(CI,64.83,79.22%)。在亚组分析中,在奥罗米亚州进行的研究中观察到最高估计值(80.29%),而在南部民族地区的研究中观察到68.63%的人为68.63%。没有充血性心力衰竭的儿童比同龄人康复的可能性高4.88倍(OR,4.88; 95%CI,2.246,10.586)。结论埃塞俄比亚治疗性喂养单元上的严重急性营养不良儿童的康复率处于国际最小范围之内。因此,医护人员应加强对严重急性营养不良的管理,以及对其他合并症(如充血性心力衰竭)的管理。系统审查注册PROSPERO CRD42019119124。
更新日期:2019-12-13
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