Myocardial infarction (MI) is one of leading diseases to contribute to annual death rate of 5% in the world. In the past decades, significant work has been devoted to this subject. Biomechanics of infarcted left ventricle (LV) is associated with MI diagnosis, understanding of remodelling, MI micro-structure and biomechanical property characterizations as well as MI therapy design and optimization, but the subject has not been reviewed presently. In the article, biomechanics of infarcted LV was reviewed in terms of experiments achieved in the subject so far. The concerned content includes experimental remodelling, kinematics and kinetics of infarcted LVs. A few important issues were discussed and several essential topics that need to be investigated further were summarized. Microstructure of MI tissue should be observed even carefully and compared between different methods for producing MI scar in the same animal model, and eventually correlated to passive biomechanical property by establishing innovative constitutive laws. More uniaxial or biaxial tensile tests are desirable on MI, border and remote tissues, and viscoelastic property identification should be performed in various time scales. Active contraction experiments on LV wall with MI should be conducted to clarify impaired LV pumping function and supply necessary data to the function modelling. Pressure-volume curves of LV with MI during diastole and systole for the human are also desirable to propose and validate constitutive laws for LV walls with MI.

心肌梗塞（MI）是导致世界每年5％死亡率的主要疾病之一。在过去的几十年中，致力于该主题的大量工作。梗死的左心室（LV）的生物力学与MI诊断，对重塑的理解，MI的微结构和生物力学特性表征以及MI疗法的设计和优化有关，但目前尚未对此主题进行审查。在本文中，根据迄今为止在该受试者中完成的实验对梗塞性左室的生物力学进行了回顾。有关内容包括梗死左室的实验重塑，运动学和动力学。讨论了一些重要问题，并总结了一些需要进一步研究的基本主题。甚至应仔细观察MI组织的微观结构，并在同一动物模型中对产生MI疤痕的不同方法进行比较，并最终通过建立创新的本构定律将其与被动生物力学特性相关联。希望在MI，边界和远端组织上进行更多的单轴或双轴拉伸试验，并且应在不同的时间范围内进行粘弹性的鉴定。应当在具有MI的LV壁上进行主动收缩实验，以阐明受损的LV泵功能并为功能建模提供必要的数据。对于人的心脏舒张期和收缩期，LV与MI的压力-体积曲线对于提出和验证具有MI的LV壁的本构定律也是理想的。并通过建立创新的本构定律最终与被动生物力学特性相关联。希望在MI，边界和远端组织上进行更多的单轴或双轴拉伸试验，并且应在不同的时间范围内进行粘弹性的鉴定。应当在具有MI的LV壁上进行主动收缩实验，以阐明受损的LV泵功能并为功能建模提供必要的数据。对于人的心脏舒张期和收缩期，LV与MI的压力-体积曲线对于提出和验证具有MI的LV壁的本构定律也是理想的。并通过建立创新的本构定律最终与被动生物力学特性相关联。在MI，边界组织和远端组织上需要进行更多的单轴或双轴拉伸试验，并且应在不同的时间范围内进行粘弹性的鉴定。应当在具有MI的LV壁上进行主动收缩实验，以阐明受损的LV泵功能并为功能建模提供必要的数据。对于人的心脏舒张期和心脏收缩期，LV与MI的压力-容积曲线对于提出和验证具有MI的LV壁的本构律也是理想的。应当在具有MI的LV壁上进行主动收缩实验，以阐明受损的LV泵功能并为功能建模提供必要的数据。对于人的心脏舒张期和收缩期，LV与MI的压力-体积曲线对于提出和验证具有MI的LV壁的本构定律也是理想的。应当在具有MI的LV壁上进行主动收缩实验，以阐明受损的LV泵功能并为功能建模提供必要的数据。对于人的心脏舒张期和收缩期，LV与MI的压力-体积曲线对于提出和验证具有MI的LV壁的本构定律也是理想的。