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Lanostane triterpenoids from cultivated fruiting bodies of the wood-rot basidiomycete Ganoderma casuarinicola
Phytochemistry ( IF 3.2 ) Pub Date : 2020-02-01 , DOI: 10.1016/j.phytochem.2019.112225 Masahiko Isaka 1 , Panida Chinthanom 1 , Pranee Rachtawee 1 , Wilunda Choowong 1 , Rattaket Choeyklin 1 , Tuksaporn Thummarukcharoen 1
Phytochemistry ( IF 3.2 ) Pub Date : 2020-02-01 , DOI: 10.1016/j.phytochem.2019.112225 Masahiko Isaka 1 , Panida Chinthanom 1 , Pranee Rachtawee 1 , Wilunda Choowong 1 , Rattaket Choeyklin 1 , Tuksaporn Thummarukcharoen 1
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Sixteen previously undescribed lanostane-type triterpenoids (1-16), together with fourteen known compounds, were isolated from cultivated fruiting bodies of the basidiomycete Ganoderma casuarinicola, a recently described species. The structures were elucidated on the basis of NMR spectroscopic and mass spectrometry data. Two of these compounds, 9 and 10, showed antimalarial activity with IC50 values of 9.7 and 9.2 μg/ml, respectively.
中文翻译：
来自木腐担子菌 Ganoderma casuarinicola 栽培子实体的羊毛甾烷三萜类化合物
十六种以前未描述的羊毛脂烷型三萜类化合物 (1-16) 以及十四种已知化合物从担子菌 Ganoderma casuarinicola（一种最近描述的物种）的栽培子实体中分离出来。基于NMR光谱和质谱数据阐明了结构。其中两种化合物 9 和 10 显示出抗疟活性，IC50 值分别为 9.7 和 9.2 μg/ml。
更新日期：2020-02-01
中文翻译：
来自木腐担子菌 Ganoderma casuarinicola 栽培子实体的羊毛甾烷三萜类化合物
十六种以前未描述的羊毛脂烷型三萜类化合物 (1-16) 以及十四种已知化合物从担子菌 Ganoderma casuarinicola（一种最近描述的物种）的栽培子实体中分离出来。基于NMR光谱和质谱数据阐明了结构。其中两种化合物 9 和 10 显示出抗疟活性，IC50 值分别为 9.7 和 9.2 μg/ml。
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