Atherosclerosis within 2 or more arterial beds has been termed polyvascular disease. Although polyvascular disease has long been associated with heightened cardiovascular risk, much is still unknown regarding its pathophysiology and management. In this past decade, the field of cardiovascular disease has experienced exponential growth in terms of antithrombotic and lipid-lowering therapies aimed at mitigating ischemic events. This review describes the inherent risk associated with polyvascular disease in contemporary observational and clinical trial populations and summarizes novel therapies in this high-risk population.

中文翻译：

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多血管疾病：对当前临床状况的重新评估。

2个或更多动脉床内的动脉粥样硬化被称为多血管疾病。尽管多血管疾病长期以来一直与心血管风险增加有关，但在其病理生理学和治疗方法方面仍不清楚。在过去的十年中，针对旨在减轻缺血事件的抗血栓和降脂疗法，心血管疾病领域经历了指数增长。这篇综述描述了当代观察和临床试验人群中与多血管疾病相关的固有风险，并总结了这一高风险人群中的新疗法。