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Gender and Age Differences in the Suppressive Effect of a 50 Hz Electric Field on the Immobilization-Induced Increase of Plasma Glucocorticoid in Mice.
Bioelectromagnetics ( IF 1.8 ) Pub Date : 2019-12-12 , DOI: 10.1002/bem.22238
Shinji Harakawa 1, 2 , Takuya Hori 1, 2 , Takaki Nedachi 2 , Hiroshi Suzuki 1
Affiliation  

We developed an experimental system to characterize the suppressive effect of extremely low-frequency (ELF) electric fields (EFs) on the stress response. We assessed differences in the EF effects by age and gender. Control, EF-alone, immobilization-alone, and co-treated groups were subjected to an EF (50 Hz, 10 kV/m). Co-treated mice were exposed to the EF for 60 min, with immobilization during the latter half. Our results indicate that the suppressive effects of ELF EFs on the stress response in immobilized mice occur regardless of gender or age. As stress plays an important role in the onset and progression of various diseases, these findings may have broad implications for understanding the efficacy of EFs in animal, and perhaps human, health. Bioelectromagnetics. 2020;41:156-163. © 2019 Bioelectromagnetics Society.

中文翻译:

性别和年龄的差异,在50 Hz电场抑制小鼠血浆中血浆糖皮质激素的增加所引起的抑制作用。

我们开发了一个实验系统来表征极低频(ELF)电场(EFs)对应力响应的抑制作用。我们按年龄和性别评估了EF影响的差异。对照组,仅EF,单独固定和共同治疗的组接受EF(50 Hz,10 kV / m)。将共同治疗的小鼠暴露于EF 60分钟,并在后半段固定。我们的结果表明,不论性别或年龄,ELF EF对固定化小鼠应激反应的抑制作用均会发生。由于压力在各种疾病的发作和发展中起着重要作用,因此这些发现可能对理解EF在动物乃至人类健康中的功效具有广泛的意义。生物电磁学。2020; 41:156-163。©2019生物电磁学会。
更新日期:2020-01-17
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