Following the invention of spectacles in the 13th century, the correction of presbyopia became one of the most important challenges faced by those concerned with the optimization of vision. It is estimated that approximately 30% of the whole world population is presbyopic, the proportion rising to nearly 50% in some developed countries.1,2 The inadequate amplitude of accommodation that characterizes uncorrected presbyopia reduces our ability to perform a wide range of daily near visual tasks. This visual disability that we suffer after reaching an age of approximately 40 years affects the

中文翻译：

---

矫正老花眼的药理策略。

随着13世纪眼镜的发明，老花眼的矫正已成为关注视力优化的人们所面临的最重要挑战之一。据估计，全世界约有30％的老花眼，在某些发达国家中这一比例上升到将近50％。1,2适应性不足的振幅表征了未矫正的老花眼，这降低了我们在近距离进行各种日常活动的能力。视觉任务。我们在达到约40岁后遭受的这种视力障碍会影响到