Pigeon Fancier's Lung (PFL) is a form of Hypersensitivity Pneumonitis where lung pathology occurs due to an immune reaction to repeated inhalation of large amounts of feather-derived and droppings-derived dust [1]. The 1μm dust particles penetrate the lower respiratory tract, initiating characteristic granulomatous inflammation in distal airways and alveoli. The particles, which carry pigeon antigens, cause irritation, and likely contain microbial components, both of which enhance immunogenicity.

中文翻译：

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针对禽类和微生物抗原的抗体和 T 细胞反应与种鸽者的过敏性肺炎疾病参数相关

Pigeon Fancier's Lung (PFL) 是一种过敏性肺炎，其中肺部病变是由于反复吸入大量羽毛来源和粪便来源的灰尘而引起的免疫反应 [1]。1μm 的灰尘颗粒穿透下呼吸道，在远端气道和肺泡中引发特征性肉芽肿性炎症。携带鸽子抗原的颗粒会引起刺激，并且可能含有微生物成分，这两种成分都会增强免疫原性。