Simple methods to incorporate deuterium into organic compounds are highly sought after as deuteration can enable mechanistic studies or improve the metabolic stability of pharmaceuticals. Now, a catalytic hydrogen–deuterium exchange reaction using deuterated water allows convenient access to deuterated aldehyde building blocks.

中文翻译：

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从重水到重醛

由于氘能实现机理研究或改善药物的代谢稳定性，因此非常需要将氘掺入有机化合物的简单方法。现在，使用氘化水的催化氢-氘交换反应可以方便地获得氘化醛的结构单元。