There is a constant and consistent message in the medical and lay press that obesity is a modern epidemic affecting the developed world. It causes and exacerbates multiple diseases including cardio-metabolic, musculoskeletal, cancer and respiratory diseases [1]. There is no doubt that improving diet and lifestyle to eliminate obesity has positive health benefits [1]. Although this truism is well-known and accepted, the impact of obesity on the immunobiology of disease [1–4] is only beginning to be unravelled and this might reveal more subtle, albeit profound, effects of obesity on chronic inflammatory diseases. Adipose tissue is increased around the airway in asthma and is associated with BMI, airway inflammation and disease severity. Fat in the airway might contribute both positively and negatively to the immunobiology of asthma. http://bit.ly/2CgOGsY

中文翻译：

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脂肪气道：好脂肪和坏脂肪的来源？

医学和非专业媒体一直在传达一个信息，即肥胖是一种影响发达国家的现代流行病。它会导致并加剧多种疾病，包括心脏代谢、肌肉骨骼、癌症和呼吸系统疾病[1]。毫无疑问，改善饮食和生活方式以消除肥胖对健康有益[1]。尽管这一真理已广为人知并被接受，但肥胖对疾病免疫生物学的影响 [1-4] 才刚刚开始被阐明，这可能揭示肥胖对慢性炎症疾病的更微妙但意义深远的影响。哮喘患者气道周围的脂肪组织增加，并且与 BMI、气道炎症和疾病严重程度有关。气道中的脂肪可能对哮喘的免疫生物学产生积极和消极的影响。http://位。