EGCG is an important bioactive component of green tea, which has the biological functions of antioxidant and antitumor. However, the stability of EGCG is poor, the absorption rate is low, and the bioavailability needs to be improved. In this study, the factors influencing the bioavailability of oral EGCG and the commonly used methods to improve its bioavailability were reviewed. The results showed that oral EGCG was not stable in intestinal and blood environment, most of EGCG was not absorbed, and its bioavailability was reduced. However, the bioavailability of oral EGCG could be significantly improved by modifying the structure of EGCG or the protection and delivery through nano-materials. It provided a reference for further research and development of tea polyphenol-related products.

EGCG是绿茶的重要生物活性成分，具有抗氧化和抗肿瘤的生物学功能。但是，EGCG的稳定性差，吸收率低，需要提高生物利用度。在这项研究中，综述了影响口服EGCG生物利用度的因素以及提高其生物利用度的常用方法。结果表明，口服EGCG在肠道和血液环境中不稳定，大部分EGCG不被吸收，其生物利​​用度降低。但是，通过改变EGCG的结构或通过纳米材料的保护和递送，可以显着提高口服EGCG的生物利用度。为进一步研究茶多酚相关产品提供了参考。