We seek a neural circuit explanation for sensory-motor reaction times. In the smooth eye movement region of the frontal eye fields (FEFSEM), the latencies of pairs of neurons show trial-by-trial correlations that cause trial-by-trial correlations in neural and behavioral latency. These correlations can account for two-third of the observed variation in behavioral latency. The amplitude of preparatory activity also could contribute, but the responses of many FEFSEM neurons fail to support predictions of the traditional "ramp-to-threshold" model. As a correlate of neural processing that determines reaction time, the local field potential in FEFSEM includes a brief wave in the 5-15-Hz frequency range that precedes pursuit initiation and whose phase is correlated with the latency of pursuit in individual trials. We suggest that the latency of the incoming visual motion signals combines with the state of preparatory activity to determine the latency of the transient response that controls eye movement. IMPACT STATEMENT The motor cortex for smooth pursuit eye movements contributes to sensory-motor reaction time through the amplitude of preparatory activity and the latency of transient, visually driven responses.

中文翻译：

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感觉运动行为中反应延迟的神经基础。

我们寻求感觉运动反应时间的神经回路解释。在额叶视野的平滑眼球运动区域 (FEFSEM)，神经元对的潜伏期显示出逐次试验的相关性，导致神经和行为潜伏期的逐次试验相关性。这些相关性可以解释观察到的行为潜伏期变化的三分之二。准备活动的幅度也可能有所贡献，但许多 FEFSEM 神经元的反应无法支持传统的“斜坡到阈值”模型的预测。作为决定反应时间的神经处理的相关因素，FEFSEM 中的局部场电位包括一个 5-15-Hz 频率范围内的短波，该波先于追踪开始，其相位与单个试验中的追踪延迟相关。我们建议将传入的视觉运动信号的延迟与准备活动的状态相结合，以确定控制眼球运动的瞬态响应的延迟。影响陈述 用于平滑追踪眼球运动的运动皮层通过准备活动的幅度和短暂的、视觉驱动的反应的潜伏期有助于感觉运动反应时间。