Niobium oxide coatings deposited on Ti₆Al₄V substrates by electron beam deposition and annealed in air at 600 °C and 800 °C were evaluated for their suitability towards dental, maxillofacial or orthopaedic implant applications. A detailed physico-chemical properties investigation was carried out in order to determine their elemental and phase composition, surface morphology and roughness, mechanical properties, wettability, and corrosion resistance in simulated body fluid solution (pH = 7.4) at room temperature. The biocompatibility of the bare Ti₆Al₄V substrate and coated surfaces was evaluated by testing the cellular adhesion and viability/proliferation of human osteosarcoma cells (MG-63) after 72 h of incubation. The coatings annealed at 800 °C exhibit more phase pure nanocrystalline Nb₂O₅ surfaces with enhanced wettability, reduced porosity and enhanced corrosion resistance properties making them good candidate for dental, maxillofacial or orthopaedic implant applications.

评估了通过电子束沉积在Ti ₆ Al ₄ V基底上沉积并在600°C和800°C的空气中退火的氧化铌涂层在牙科，颌面或整形外科植入物中的适用性。为了确定它们的元素和相组成，表面形态和粗糙度，机械性能，润湿性和室温下在模拟体液溶液（pH = 7.4）中的耐腐蚀性，进行了详细的理化性质研究。裸露的Ti ₆ Al ₄的生物相容性在孵育72小时后，通过测试人骨肉瘤细胞（MG-63）的细胞粘附性和生存力/增殖来评估V底物和涂层表面。在800°C退火的涂层显示出更多的相纯纳米晶Nb ₂ O ₅表面，具有增强的润湿性，降低的孔隙率和增强的耐腐蚀性，使其成为牙科，颌面或整形外科植入物应用的理想选择。