Background and Purpose- Studies indicate that consuming breakfast every day, and particularly oatmeal, is associated with lower risk of stroke. However, few studies have considered replacement foods when considering foods usually consumed at breakfast. We, therefore, aimed to model substitutions between the breakfast food products oatmeal, eggs, yogurt, or white bread and subsequent risk of stroke. Methods- Participants from the Danish cohort study (Diet, Cancer and Health; n=55 095) were followed for 13.4 years, during which 2260 subjects experienced a first-ever stroke. Breakfast foods were assessed using a validated 192-item food-frequency questionnaire at baseline. Cox proportional hazards models were used to estimate adjusted hazard ratios and 95% CIs for associations between hypothetical substitutions of standard portion sizes of breakfast foods and stroke. Results- Modeling replacement of white bread or eggs with oatmeal was associated with a lower rate of total stroke (hazard ratio [HR]=0.96 [95% CI, 0.95-0.98]; HR=0.96 [95% CI, 0.93-0.98], respectively), total ischemic stroke (HR=0.96 [95% CI, 0.94-0.98]; HR=0.96 [95% CI, 0.94-0.99], respectively), and ischemic stroke due to small-artery occlusion (HR=0.95 [95% CI, 0.93-0.98]; HR=0.95 [95% CI, 0.91-0.99], respectively). Furthermore, modeling replacement of eggs with oatmeal was associated with a lower rate of total hemorrhagic stroke (HR=0.94 [95% CI, 0.89-0.99]). Modeling replacement of yogurt with oatmeal was not associated with stroke. Conclusions- Our findings suggest that a diet containing oatmeal instead of white bread or eggs may be associated with a lower rate of stroke.

中文翻译：

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替代燕麦片和早餐食品和中风率。

背景和目的-研究表明，每天食用早餐，尤其是燕麦片，可降低中风的风险。但是，很少有研究在考虑通常在早餐时食用的食物时考虑过补充食物。因此，我们旨在模拟早餐食品中的燕麦片，鸡蛋，酸奶或白面包之间的替代以及随后的中风风险。方法-丹麦队列研究（饮食，癌症和健康； n = 55095）的参与者被随访了13.4年，在此期间有2260名受试者经历了有史以来的首次中风。在基线时，使用经过验证的192个食品频率问卷对早餐食品进行了评估。使用Cox比例风险模型来估计调整后的风险比和95％CI，以作为早餐食品的标准份量和中风的假设替代之间的关联。结果-用燕麦片代替白面包或鸡蛋的模型与总卒中发生率较低相关（危险比[HR] = 0.96 [95％CI，0.95-0.98]； HR = 0.96 [95％CI，0.93-0.98] ，总缺血性卒中（HR = 0.96 [95％CI，0.94-0.98]; HR = 0.96 [95％CI，0.94-0.99]）和因小动脉闭塞引起的缺血性卒中（HR = 0.95） [95％CI，0.93-0.98]； HR = 0.95 [95％CI，0.91-0.99]。此外，用燕麦代替鸡蛋的模型化与总出血性卒中发生率降低有关（HR = 0.94 [95％CI，0.89-0.99]）。用燕麦片代替酸奶的建模与中风无关。