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A Simple Near-Infrared Fluorescent Probe for the Detection of Peroxynitrite.
ChemistryOpen ( IF 2.5 ) Pub Date : 2019-12-09 , DOI: 10.1002/open.201900301 Luling Wu 1 , Xue Tian 1 , Hai-Hao Han 2 , Jie Wang 2 , Robin R Groleau 1 , Paramabhorn Tosuwan 3 , Boontana Wannalerse 3 , Adam C Sedgwick 4 , Steven D Bull 1 , Xiao-Peng He 2 , Tony D James 1
ChemistryOpen ( IF 2.5 ) Pub Date : 2019-12-09 , DOI: 10.1002/open.201900301 Luling Wu 1 , Xue Tian 1 , Hai-Hao Han 2 , Jie Wang 2 , Robin R Groleau 1 , Paramabhorn Tosuwan 3 , Boontana Wannalerse 3 , Adam C Sedgwick 4 , Steven D Bull 1 , Xiao-Peng He 2 , Tony D James 1
Affiliation
Herein, we report the evaluation and synthesis of a reaction based fluorescent probe DCM‐Bpin for the detection of Peroxynitrite (ONOO−). DCM‐Bpin exhibits selective fluorescence off‐on response for ONOO− over other reactive oxygen species, including H2O2. Moreover, DCM‐Bpin is biocompatible and has been used to visualize exogenous ONOO− in HeLa cells.
中文翻译:
一种用于检测过氧亚硝酸盐的简单近红外荧光探针。
本文中,我们报告了基于反应的荧光探针DCM-Bpin的检测和评估,用于检测过氧亚硝酸盐(ONOO-)。DCM-BPIN表现出选择性的荧光断-通响应对ONOO -在其它反应性氧物质,含H的2 ö 2。此外,DCM-BPIN是生物相容的,并已用于可视化的外源性ONOO -在HeLa细胞中。
更新日期:2019-12-09
中文翻译:
一种用于检测过氧亚硝酸盐的简单近红外荧光探针。
本文中,我们报告了基于反应的荧光探针DCM-Bpin的检测和评估,用于检测过氧亚硝酸盐(ONOO-)。DCM-BPIN表现出选择性的荧光断-通响应对ONOO -在其它反应性氧物质,含H的2 ö 2。此外,DCM-BPIN是生物相容的,并已用于可视化的外源性ONOO -在HeLa细胞中。