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A Simple Near-Infrared Fluorescent Probe for the Detection of Peroxynitrite.
ChemistryOpen ( IF 2.5 ) Pub Date : 2019-12-09 , DOI: 10.1002/open.201900301
Luling Wu 1 , Xue Tian 1 , Hai-Hao Han 2 , Jie Wang 2 , Robin R Groleau 1 , Paramabhorn Tosuwan 3 , Boontana Wannalerse 3 , Adam C Sedgwick 4 , Steven D Bull 1 , Xiao-Peng He 2 , Tony D James 1
Affiliation  

Herein, we report the evaluation and synthesis of a reaction based fluorescent probe DCM‐Bpin for the detection of Peroxynitrite (ONOO−). DCM‐Bpin exhibits selective fluorescence off‐on response for ONOO over other reactive oxygen species, including H2O2. Moreover, DCM‐Bpin is biocompatible and has been used to visualize exogenous ONOO in HeLa cells.

中文翻译:

一种用于检测过氧亚硝酸盐的简单近红外荧光探针。

本文中,我们报告了基于反应的荧光探针DCM-Bpin的检测和评估,用于检测过氧亚硝酸盐(ONOO-)。DCM-BPIN表现出选择性的荧光断-通响应对ONOO -在其它反应性氧物质,含H的2 ö 2。此外,DCM-BPIN是生物相容的,并已用于可视化的外源性ONOO -在HeLa细胞中。
更新日期:2019-12-09
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