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Chemoenzymatic Synthesis of Sertraline
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2020-01-17 , DOI: 10.1002/ejoc.201901810 Lisa Marx 1, 2, 3 , Nicolás Ríos-Lombardía 2 , Philipp Süss 3 , Matthias Höhne 4 , Francisco Morís 2 , Javier González-Sabín 2 , Per Berglund 1
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2020-01-17 , DOI: 10.1002/ejoc.201901810 Lisa Marx 1, 2, 3 , Nicolás Ríos-Lombardía 2 , Philipp Süss 3 , Matthias Höhne 4 , Francisco Morís 2 , Javier González-Sabín 2 , Per Berglund 1
Affiliation
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A chemoenzymatic approach has been developed for the preparation of sertraline, an established anti-depressant drug. Ketoreductases (KREDs) were employed to yield a key chiral precursor. The biored ...
中文翻译：
舍曲林的化学酶法合成
已经开发了一种化学酶促方法来制备舍曲林，一种成熟的抗抑郁药。酮还原酶 (KRED) 用于产生关键的手性前体。生物红...
更新日期：2020-01-17
中文翻译：
舍曲林的化学酶法合成
已经开发了一种化学酶促方法来制备舍曲林，一种成熟的抗抑郁药。酮还原酶 (KRED) 用于产生关键的手性前体。生物红...
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