Bacterial pathogens secrete effector proteins to manipulate host signaling proteins and cellular structures. In this issue of Cell Host & Microbe, Pagliuso et al. (2019) propose an effector mechanism in Listeria monocytogenes whereby an RNA-binding protein associates with bacterial RNA that stimulates RIG-I (retinoic acid inducible gene I)-based innate immunity in the host cytosol.

中文翻译：

---

细菌效应机制中的RNA惊喜。

细菌病原体分泌效应蛋白来操纵宿主信号蛋白和细胞结构。在本期《细胞宿主与微生物》中，Pagliuso等人。（2019）提出了一种单核细胞增生李斯特菌的效应子机制，即一种RNA结合蛋白与细菌RNA缔合，从而刺激宿主细胞质中基于RIG-I（视黄酸诱导基因I）的先天免疫力。