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Emerging from the Shadow of Hemagglutinin: Neuraminidase Is an Important Target for Influenza Vaccination.
Cell Host & Microbe ( IF 20.6 ) Pub Date : 2019-12-11 , DOI: 10.1016/j.chom.2019.11.006
Florian Krammer 1 , Lei Li 2 , Patrick C Wilson 2
Affiliation  

Gilchuk et al. (2019) and Zhu et al. (2019) provide detailed structural information about epitopes on influenza virus N9 neuraminidase and characterize breadth, potency, mechanism of action, and in vivo protective effects of human antibodies targeting these epitopes. The findings highlight the importance of neuraminidase as a target for improved influenza virus vaccines.

中文翻译:

从血凝素的阴影中出现:神经氨酸酶是流感疫苗的重要靶标。

Gilchuk等。(2019)和Zhu等。(2019)提供了有关流感病毒N9神经氨酸酶表位的详细结构信息,并表征了针对这些表位的人类抗体的广度,效力,作用机制和体内保护作用。这些发现突出了神经氨酸酶作为改良流感病毒疫苗靶标的重要性。
更新日期:2019-12-11
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