CHIMGEN: a Chinese imaging genetics cohort to enhance cross-ethnic and cross-geographic brain research.,Molecular Psychiatry

当前位置： X-MOL 学术 › Mol. Psychiatry › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

CHIMGEN: a Chinese imaging genetics cohort to enhance cross-ethnic and cross-geographic brain research.
Molecular Psychiatry ( IF 9.6 ) Pub Date : 2019-12-11 , DOI: 10.1038/s41380-019-0627-6
Qiang Xu ₁ , Lining Guo ₁ , Jingliang Cheng ₂ , Meiyun Wang _{3,

4} , Zuojun Geng ₅ , Wenzhen Zhu ₆ , Bing Zhang ₇ , Weihua Liao _{8,

9} , Shijun Qiu ₁₀ , Hui Zhang ₁₁ , Xiaojun Xu ₁₂ , Yongqiang Yu ₁₃ , Bo Gao ₁₄ , Tong Han _{15,

16} , Zhenwei Yao ₁₇ , Guangbin Cui ₁₈ , Feng Liu ₁ , Wen Qin ₁ , Quan Zhang ₁ , Mulin Jun Li ₁₉ , Meng Liang ₂₀ , Feng Chen ₂₁ , Junfang Xian ₂₂ , Jiance Li ₂₃ , Jing Zhang ₂₄ , Xi-Nian Zuo _{25,

26} , Dawei Wang ₂₇ , Wen Shen ₂₈ , Yanwei Miao ₂₉ , Fei Yuan ₃₀ , Su Lui _{31,

32} , Xiaochu Zhang _{33,

34} , Kai Xu _{35,

36} , Long Jiang Zhang ₃₇ , Zhaoxiang Ye ₃₈ , Chunshui Yu _{1,

39} ,

Affiliation

Department of Radiology and Tianjin Key Laboratory of Functional Imaging, Tianjin Medical University General Hospital, 300052, Tianjin, China.
Department of Magnetic Resonance Imaging, The First Affiliated Hospital of Zhengzhou University, 450052, Zhengzhou, China.
Department of Radiology, Zhengzhou University People's Hospital and Henan Provincial People's Hospital, 450003, Zhengzhou, China.
Henan Key Laboratory for Medical Imaging of Neurological Diseases, 450003, Zhengzhou, China.
Department of Medical Imaging, The Second Hospital of Hebei Medical University, 050000, Shijiazhuang, China.
Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430030, Wuhan, China.
Department of Radiology, Drum Tower Hospital, Medical School of Nanjing University, 210008, Nanjing, China.
Department of Radiology, Xiangya Hospital, Central South University, 410008, Changsha, China.
National Clinical Research Center for Geriatric Disorder, 410008, Changsha, China.
Department of Medical Imaging, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, 510405, Guangzhou, China.
Department of Radiology, The First Hospital of Shanxi Medical University, 030001, Taiyuan, China.
Department of Radiology, The Second Affiliated Hospital of Zhejiang University, School of Medicine, 310009, Hangzhou, China.
Department of Radiology, The First Affiliated Hospital of Anhui Medical University, 230022, Hefei, China.
Department of Radiology, Yantai Yuhuangding Hospital, 264000, Yantai, China.
Department of Radiology, Tianjin Huanhu Hospital, 300350, Tianjin, China.
Tianjin Key Laboratory of Cerebral Vascular and Neurodegenerative Diseases, 300350, Tianjin, China.
Department of Radiology, Huashan Hosptial, Fudan University, 200040, Shanghai, China.
Functional and Molecular Imaging Key Lab of Shaanxi Province & Department of Radiology, Tangdu Hospital, The Military Medical University of PLA Airforce (Fourth Military Medical University), 710038, Xi'an, China.
Collaborative Innovation Center of Tianjin for Medical Epigenetics, Tianjin Key Laboratory of Medical Epigenetics, School of Basic Medical Sciences, Tianjin Medical University, 300070, Tianjin, China.
School of Medical Imaging, Tianjin Medical University, 300203, Tianjin, China.
Department of Radiology, Hainan General Hospital, 570311, Haikou, China.
Department of Radiology, Beijing Tongren Hospital, Capital Medical University, 100730, Beijing, China.
Department of Radiology, The First Affiliated Hospital of Wenzhou Medical University, 325000, Wenzhou, China.
Department of Magnetic Resonance, Lanzhou University Second Hospital, 730050, Lanzhou, China.
Department of Psychology, University of Chinese Academy of Sciences (CAS), 100049, Beijing, China.
CAS Key Laboratory of Behavioral Science, Institute of Psychology, 100101, Beijing, China.
Department of Radiology, Qilu Hospital of Shandong University, 250012, Jinan, China.
Department of Radiology, Tianjin First Center Hospital, 300192, Tianjin, China.
Department of Radiology, The First Affiliated Hospital of Dalian Medical University, 116011, Dalian, China.
Department of Radiology, Pingjin Hospital, Logistics University of Chinese People's Armed Police Forces, 300162, Tianjin, China.
Department of Radiology, The Center for Medical Imaging, West China Hospital of Sichuan University, 610041, Chengdu, China.
Department of Radiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 325000, Wenzhou, China.
CAS Key Laboratory of Brain Function and Disease, University of Science and Technology of China, 230026, Hefei, China.
School of Life Sciences, University of Science & Technology of China, 230026, Hefei, China.
Department of Radiology, The Affiliated Hospital of Xuzhou Medical University, 221006, Xuzhou, China.
School of Medical Imaging, Xuzhou Medical University, 221004, Xuzhou, China.
Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, 210002, Nanjing, China.
Department of Radiology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, 300060, Tianjin, China.
CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, 200031, China.

The Chinese Imaging Genetics (CHIMGEN) study establishes the largest Chinese neuroimaging genetics cohort and aims to identify genetic and environmental factors and their interactions that are associated with neuroimaging and behavioral phenotypes. This study prospectively collected genomic, neuroimaging, environmental, and behavioral data from more than 7000 healthy Chinese Han participants aged 18-30 years. As a pioneer of large-sample neuroimaging genetics cohorts of non-Caucasian populations, this cohort can provide new insights into ethnic differences in genetic-neuroimaging associations by being compared with Caucasian cohorts. In addition to micro-environmental measurements, this study also collects hundreds of quantitative macro-environmental measurements from remote sensing and national survey databases based on the locations of each participant from birth to present, which will facilitate discoveries of new environmental factors associated with neuroimaging phenotypes. With lifespan environmental measurements, this study can also provide insights on the macro-environmental exposures that affect the human brain as well as their timing and mechanisms of action.

更新日期：2019-12-11

点击分享查看原文

点击收藏

公开下载

阅读更多本刊最新论文本刊介绍/投稿指南11