Advanced antimicrobial agents that treat infectious diseases are greatly needed. Various silver-based nanomaterials have been developed and are considered potential candidates for many commercial products, but they lack durability and adequate antibacterial activity. A new class of nanohybrids of silver nanoparticles (AgNPs) grown in-situ on graphene oxide (GO) using a silver ion salt was synthesized by a simple ultrasonic mixing method. The structure and composition of the nanohybrids were investigated by SEM, TEM, FTIR, TGA, XRD and XPS. Results indicated that GO acts not only as a negatively charged macromolecule for capturing Ag⁺ ions, but also a reducing agent to reduce the Ag⁺ ions to AgNPs. The heterogeneous structure leads to abundant well-dispersed AgNPs and Ag⁺ ions on the GO support. The as-prepared nanohybrids make full use of the advantages of both AgNPs and GO-Ag⁺ salts, leading to improved and long-term antibacterial activity against both S.aureus and E. coli.

非常需要用于治疗传染病的高级抗菌剂。已经开发了各种基于银的纳米材料，它们被认为是许多商业产品的潜在候选者，但是它们缺乏耐用性和足够的抗菌活性。通过一种简单的超声混合方法，合成了一类新型的纳米银杂化物，即使用银离子盐在氧化石墨烯（GO）上原位生长的银纳米粒子（AgNPs）。通过SEM，TEM，FTIR，TGA，XRD和XPS对纳米杂化物的结构和组成进行了研究。结果表明，GO不仅充当捕获Ag ⁺离子的带负电荷的大分子，而且还充当将Ag ⁺离子还原成AgNPs的还原剂。异质结构导致大量分散良好的AgNP和Ag ⁺离子在GO支座上。所制备的纳米复合物充分利用两者的AgNPs和GO-Ag的优点⁺盐，导致对两者改进的和长期抗菌活性的金黄色葡萄球菌和大肠杆菌。