Abstract The paper presents template strategy using siloxane-acrylate latex and its modified form to prepare nanostructured calcium silicate (wollastonite) containing nanosized gold and regular porosity. Optimal conditions for the annealing of silicate xerogel were outlined leading to nanoporous wollastonite with minimal porous defects (pore size corresponds to latex particles 150–200 nm). The fabrication of nanostructured wollastonite ceramics was suggested to use spark plasma sintering (SPS). The formation of porous ceramic framework (compressive strength ∼ 120 MPa) via SPS consolidation of silicate xerogel (xonotlite) contained latex template (poreformer), a feature of the method for wollastonite template synthesis. The ceramic wollastonite samples have been implanted into ICR/CD1 mice to test the toxicity of the material “in vivo”. The results are of great interest for the preparation of high-quality biomaterials for modern medicine using simple technological approaches and available raw materials.

中文翻译：

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合成 CaSiO3 溶胶-凝胶粉末和 SPS 陶瓷衍生物：“体内”毒性评估

摘要 本文提出了使用硅氧烷-丙烯酸酯胶乳及其改性形式制备含有纳米级金和规则孔隙的纳米结构硅酸钙（硅灰石）的模板策略。概述了硅酸盐干凝胶退火的最佳条件，导致纳米多孔硅灰石具有最小的多孔缺陷（孔径对应于 150-200 nm 的乳胶颗粒）。建议使用放电等离子体烧结 (SPS) 制造纳米结构的硅灰石陶瓷。通过含有乳胶模板（成孔剂）的硅酸盐干凝胶（硬硅钙石）的 SPS 固结形成多孔陶瓷骨架（抗压强度 ~ 120 MPa），这是硅灰石模板合成方法的一个特征。陶瓷硅灰石样品已被植入 ICR/CD1 小鼠体内，以测试该材料的“体内”毒性。