Carbon nanotubes (CNTs) are a class of carbon allotropes with interesting properties that make them productive materials for usage in various disciplines of nanotechnology such as in electronics equipments, optics and therapeutics. They exhibit distinguished properties viz., strength, and high electrical and heat conductivity. Their uniqueness can be attributed due to the bonding pattern present between the atoms which are very strong and also exhibit high extreme aspect ratios. CNTs are classified as single-walled carbon nanotubes (SWCNTs) and multi-walled carbon nanotubes (MWCNTs) on the basis of number of sidewalls present and the way they are arranged spatially. Application of CNTs to improve the performance of many products, especially in healthcare, has led to an occupational and public exposure to these nanomaterials. Hence, it becomes a major concern to analyze the issues pertaining to the toxicity of CNTs and find the best suitable ways to counter those challenges. This review summarizes the toxicity issues of CNTs in vitro and in vivo in different organ systems (bio interphases) of the body that result in cellular toxicity.

碳纳米管（CNTs）是一类具有同素性质的碳同素异形体，使它们成为可用于各种纳米技术领域（例如，电子设备，光学和治疗学）的生产材料。它们表现出杰出的性能，即强度，高电导率和热导率。它们的独特性可以归因于存在于原子之间的键结图，该键结图非常坚固，并且还显示出很高的极限长宽比。根据存在的侧壁数量及其在空间上的排列方式，CNT分为单壁碳纳米管（SWCNT）和多壁碳纳米管（MWCNT）。碳纳米管的应用提高了许多产品的性能，尤其是在医疗保健领域，已经导致职业和公众接触这些纳米材料。因此，分析与碳纳米管毒性有关的问题并找到应对这些挑战的最佳合适方法已成为一个主要问题。这篇综述总结了碳纳米管的毒性问题在体内和体内不同器官系统（生物中间相）中导致细胞毒性。