BACKGROUND Body posture may be disordered by vestibular dysfunction, neurological disorders, problems with the distribution of muscle tone, brain injuries, and other dysfunctions. Growth hormone deficiency (GHD) can lead to many disorders, particularly of the musculoskeletal system. During treatment with recombinant human growth hormone (rhGH), an increase in muscle mass and an improvement in bone structure can be observed in children suffering from hypopituitarism from GHD. METHODS The study involved 33 children suffering from hypopituitarism with GHD (9 girls and 24 boys), aged 10-14 years old. Measurements of the magnitude of their anterior-posterior spinal curvatures were made using an inclinometer. The children were examined at the medianus of the sacrum bone, the Th12-L1 intervertebral area, and the C7-Th1 intervertebral area. In order to characterize the anterior-posterior curvature of the spine, the results were compared with the general norms reported by Saunders. Statistical calculations were carried out using the statistical package Statistica 10 PL. RESULTS Lumbar lordosis angles were higher in the patients currently receiving growth hormone (GH) treatment than in those who had yet to receive it. There is a statistically significant positive correlation between the length of growth hormone treatment and the alpha angle. There are also statistically significant correlations between age at the beginning of growth hormone therapy and the angle of lordosis. Statistically significant correlations were also seen between age at the beginning of growth hormone therapy and the alpha angle. CONCLUSIONS Although there may be changes in posture at the beginning of rhGH treatment, the sooner growth hormone therapy begins, the better the body posture. The longer the growth hormone treatment, the better the posture, as expressed by the alpha angle in the sagittal plane.

中文翻译：

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评估垂体功能低下儿童的脊柱前-后弯曲。

背景技术身体姿势可能因前庭功能障碍，神经系统疾病，肌张力分布问题，脑损伤和其他功能障碍而紊乱。生长激素缺乏症（GHD）可能导致许多疾病，尤其是肌肉骨骼系统的疾病。在患有重组人生长激素（rhGH）的治疗过程中，患有GHD垂体功能减退的儿童可以观察到肌肉质量的增加和骨骼结构的改善。方法该研究涉及33名患有垂体功能低下的GHD儿童（9名女孩和24名男孩），年龄10-14岁。使用倾斜仪测量其前后脊柱弯曲的幅度。在children骨正中，Th12-L1椎间区域和C7-Th1椎间区域检查儿童。为了表征脊柱的前后弯曲度，将结果与桑德斯报告的一般规范进行了比较。使用统计软件包Statistica 10 PL进行统计计算。结果目前接受生长激素（GH）治疗的患者的腰椎前凸角度要高于尚未接受生长激素（GH）治疗的患者。生长激素治疗的时间长度和α角之间在统计学上具有显着正相关。生长激素治疗开始时的年龄与脊柱前凸角度之间也存在统计学上的显着相关性。在生长激素治疗开始时的年龄与阿尔法角之间也发现了统计学上显着的相关性。结论尽管在rhGH治疗开始时姿势可能有所改变，但生长激素治疗开始越早，身体姿势就越好。生长激素治疗的时间越长，姿势越好，如矢状面中的α角所表示。