A four-fold interpenetrated Zn(II)-based coordination polymer with the chemical formula of {[Zn₂(L)₂(bdc)]·(H₂O)₂·DMF}_n (1) was synthesized by solvent method using terephthalic acid (H₂bdc) and N1,N1,N4,N4-tetrakis(4-(1H-imidazol-1-yl)phenyl)benzene-1,4-diamine (L) as the mixed ligands. The as-prepared complex 1 was measured via the elemental analysis and single crystal X-ray diffraction. Furthermore, due to its strong intense emission, complex 1 could be applied as luminescent sensor to sensitively detect 2,4,6-trinitrophenol (TNP), which has the characteristics of high sensitivity and selectivity. In addition, to evaluate the anti-bacterial effect of compound 1 in vitro, the P.gingivalis growth curves were measured. And the relative expression of ragA and ragB was detected by RT-PCR to reveal the mechanism of the compound in the anti-infectious activity. The potential anti-infectious criteria that has been observed in the experimental measurement has been further studied by using molecular docking technique.

采用溶剂法，通过化学合成了四倍互穿的Zn（II）基配位聚合物，其化学式为{[Zn ₂（L）₂（bdc）]·（H ₂ O）₂ ·DMF} _n（1）。对苯二甲酸（H ₂ bdc）和N1，N1，N4，N4-四（4-（1H-咪唑-1-基）苯基）苯-1,4-二胺（L）作为混合配体。通过元素分析和单晶X射线衍射测量所制备的配合物1。此外，由于其强烈的强辐射，复合物1可作为发光传感器灵敏地检测2,4,6-三硝基苯酚（TNP），具有高灵敏度和高选择性的特点。另外，为了评价化合物1的体外抗菌作用，测量了牙龈卟啉单胞菌的生长曲线。通过RT-PCR检测ragA和ragB的相对表达，揭示了该化合物在抗感染活性中的作用机理。通过使用分子对接技术，对在实验测量中观察到的潜在抗感染标准进行了进一步研究。