Objective

To determine T₁ and T₂ relaxation times of healthy pancreas parenchyma at 7 T using a multi-transmit system.

Materials and methods

Twenty-six healthy subjects were scanned with a 7 T MR system using eight parallel transceiver antennas, each with two additional receive loops. A Look-Locker sequence was used to obtain images for T₁ determination, while T₂ was obtained from spin-echo images and magnetic resonance spectroscopy measurements with different echo times. T₁ and T₂ times were calculated using a mono-exponential fit of the average magnitude signal from a region of interest in the pancreas and were tested for correlation with age.

Results

The age range of the included subjects was 21–72 years. Average T₁ and T₂ relaxation times in healthy pancreas were 896 ± 149 ms, and 26.7 ± 5.3 ms, respectively. No correlation with age was found.

Conclusion

T₁ and T₂ relaxation times of the healthy pancreas were reported for 7 T, which can be used for image acquisition optimization. No significant correlations were found between age and T₁ or T₂ relaxation times of the pancreas. Considering their low standard deviation and no observable age dependence, these values may be used as a baseline to study potentially pancreatic tissue affected by disease.

中文翻译：

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使用多发射系统测量7 T时胰腺的T 1和T 2弛豫时间

客观的

为了确定使用多传输系统在7 T时健康的胰腺实质的T ₁和T ₂弛豫时间。

材料和方法

使用7个MR系统，八个平行的收发器天线对26名健康受试者进行了扫描，每个天线都有两个额外的接收环路。使用Look-Locker序列获得用于T ₁测定的图像，而T ₂是通过自旋回波图像和具有不同回波时间的磁共振波谱测量获得的。使用来自胰腺中感兴趣区域的平均幅度信号的单指数拟合来计算T ₁和T ₂倍，并测试其与年龄的相关性。

结果

纳入受试者的年龄范围为21-72岁。健康胰腺的平均T ₁和T ₂松弛时间分别为896±149 ms和26.7±5.3 ms。没有发现与年龄的相关性。

结论

据报道，健康胰腺的T ₁和T ₂弛豫时间为7 T，可用于图像采集优化。在年龄与胰腺的T ₁或T ₂松弛时间之间未发现显着相关性。考虑到它们的低标准偏差并且没有可观察到的年龄依赖性，这些值可以用作研究受疾病影响的潜在胰腺组织的基线。