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Rhaponticin as an anti-inflammatory component of rhubarb: a minireview of the current state of the art and prospects for future research
Phytochemistry Reviews ( IF 7.3 ) Pub Date : 2019-09-28 , DOI: 10.1007/s11101-019-09652-w
Joanna Kolodziejczyk-Czepas , Jan Czepas

Rhaponticin (3,3′,5-trihydroxy-4′-methoxystilbene 3-O-β-d-glucoside; synonym–rhapontin), is a stilbene compound, mainly found in various species of rhubarb (Rheum L.). The aglycone, rhapontigenin, is thought to be the biologically active form of rhaponticin. As a component of rhubarb, rhaponticin may be present in the human diet both in foods and dietary supplements. Although promising reports have been published on the various activities of rhaponticin (see: antioxidant, estrogenic, antithrombotic, anticancer and anti-inflammatory actions), no comprehensive review exists of its anti-inflammatory properties. Therefore, the aim of the present work is to summarize the existing evidence of the anti-inflammatory properties of rhaponticin and provide a prospective insight into research on this stilbenoid.



中文翻译:

罗汉果素作为大黄的消炎成分:对当前技术水平的最新回顾以及未来研究的前景

土大黄苷(3,3',5-三羟基-4'- methoxystilbene 3- ö -β- d葡糖苷;同义词-rhapontin),是芪化合物,主要存在于大黄的各种物质(大黄L.)。糖苷配基,rapontigenin,被认为是raponticin的生物活性形式。作为大黄的成分,大黄素可以在食物和膳食补充剂中存在于人类饮食中。尽管已经发表了有关Rhaponticin各种活性的有前途的报告(见:抗氧化剂,雌激素,抗血栓形成,抗癌和抗炎作用),但对其抗炎特性尚无全面的综述。因此,本工作的目的是总结关于Rhapponticin抗炎特性的现有证据,并为对该类Stilbenoid的研究提供前瞻性的见解。

更新日期:2019-09-28
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