BACKGROUND Associations of objectively assessed physical activity in different intensities and risk of developing chronic disease that requires hospital care have not yet been examined in long term population-based studies. Studies addressing the link between physical activity and sedentary time and subsequent hospital admissions are lacking. OBJECTIVE To examine the prospective associations between physical activity and sedentary time with morbidity defined as: 1) a registered main diagnosis of cardiovascular disease, cancer, type-2 diabetes, dementia, obesity or depression; 2) number of in- and outpatient hospital visits; and 3) number of in-hospital days. METHODS In total, 1220 women and men, 18-75 years, from the population-based Sweden Attitude Behaviour and Change study 2000-2001 were included. Time spent sedentary, in light-intensity physical activity and in moderate-to-vigorous physical activity, and total accelerometer counts were assessed using the ActiGraph 7164 accelerometer. Morbidity data were obtained 2016 from Swedish registers. Cox proportional hazards models estimated hazard ratios (HR) of morbidity with 95% confidence intervals (CI) and negative binomial regression estimated incidence rate ratio (IRR) with 95% CI for number of hospital visits, and length of hospital stay. RESULTS Over a follow-up of 14.4 years (SD = 1.6), 342 persons had at least one registered hospital visit due to any of the included diagnoses. Higher moderate-to-vigorous physical activity was associated with significant risk reductions for combined morbidity (all included diagnoses) (HR: 0.65, 95% CI: 0.48-0.88) and cardiovascular disease (HR: 0.52, 95% CI: 0.33-0.82). Higher total counts showed similar results, and was also associated with fewer hospital visits (IRR = 0.56, 95% CI: 0.37-0.85). Higher sedentary time increased the risk of in-hospital days. (IRR = 2.38, 95% CI: 1.20-4.74). CONCLUSION This study supports the importance of moderate-to-vigorous physical activity for preventing chronic disease that requires hospital care, especially cardiovascular disease. High volumes of sedentary behavior may increase the risk of future hospitalization. Our results support the public health message "sit less and move more".

中文翻译：

---

加速度计评估的身体活动和久坐时间，以及与慢性病和医院就诊的关联-这是一项前瞻性队列研究，随访了15年。

背景技术在长期的基于人群的研究中，尚未检查客观评估不同强度的体育活动与发展需要医院护理的慢性病风险的相关性。缺乏针对体育锻炼与久坐时间和随后入院时间之间联系的研究。目的检查体育活动和久坐时间与发病率之间的前瞻性关联：1）对心血管疾病，癌症，2型糖尿病，痴呆，肥胖或抑郁症进行注册的主要诊断；2）住院和门诊医院就诊的次数；3）住院天数。方法总共纳入了2000-2001年基于人口的瑞典态度行为与变化研究的1220名男女，年龄在18-75岁之间。久坐的时间，在光强度体育活动和中度至剧烈体育活动中，使用ActiGraph 7164加速度计评估了总的加速度计计数。发病率数据是2016年从瑞典登记处获得的。Cox比例风险模型以95％的置信区间（CI）估计发病率的危险比（HR），而以95％CI的阴性二项式回归估计发病率比率（IRR）的住院次数和住院时间。结果在14.4年的随访中（SD = 1.6），有342名患者因其中包括的任何诊断而至少进行了一次注册医院就诊。中度至剧烈运动量增加与合并症（HR：0.65，95％CI：0.48-0.88）和心血管疾病（HR：0.52，95％CI：0.33-0.82）的综合风险显着降低相关）。较高的总计数显示出相似的结果，并且也与较少的就诊次数相关（IRR = 0.56，95％CI：0.37-0.85）。久坐的时间增加了住院日的风险。（IRR = 2.38，95％CI：1.20-4.74）。结论本研究支持中度至剧烈的体育锻炼对预防需要医院护理的慢性疾病，特别是心血管疾病的重要性。久坐的行为可能会增加将来住院的风险。我们的结果支持“少坐多走”的公共卫生信息。结论本研究支持中度至剧烈的体育锻炼对预防需要医院护理的慢性疾病，特别是心血管疾病的重要性。久坐的习惯可能会增加将来住院的风险。我们的结果支持“少坐多走”的公共卫生信息。结论本研究支持中度至剧烈的体育锻炼对预防需要医院护理的慢性疾病，特别是心血管疾病的重要性。久坐的习惯可能会增加将来住院的风险。我们的结果支持“少坐多走”的公共卫生信息。