The gut commensal segmented filamentous bacterium (SFB) attaches to the ileal epithelium and potently stimulates the host immune system. Using transmission electron microscopy (TEM), we show that mouse and rat SFB are flagellated above the concave tip at the unicellular intracellular offspring (IO) stage and that flagellation occurs prior to full IO differentiation and release of IOs from SFB filaments. This finding adds a missing link to the SFB life cycle.

中文翻译：

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从 SFB 细丝释放的细胞内后代被鞭毛。

肠道共生分节丝状细菌 (SFB) 附着于回肠上皮并有效刺激宿主免疫系统。使用透射电子显微镜 (TEM)，我们显示小鼠和大鼠 SFB 在单细胞细胞内后代 (IO) 阶段的凹尖上方有鞭毛，并且在完全 IO 分化和从 SFB 细丝释放 IO 之前发生鞭毛。这一发现为 SFB 生命周期增加了一个缺失的环节。