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Three Step Synthesis of Fully and Differently Arylated Pyridines
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2020-01-17 , DOI: 10.1002/ejoc.201901663
Mao Arita 1 , Soichi Yokoyama 1, 2 , Haruyasu Asahara 1, 2, 3 , Nagatoshi Nishiwaki 1, 2
Affiliation  

Condensation of β‐(2‐pyridyl)enamine and α,β‐unsaturated ketone in the presence of FeCl3 under air afforded highly substituted pyridines. Synthesis of differently substituted pentaarylpyridines was consequently achieved via only three steps from commercially available reagents with simple experimental manipulations.
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中文翻译:

完全和不同丙烯酸化吡啶的三步合成

在空气中存在FeCl 3的情况下,β-(2-吡啶基)烯胺和α,β-不饱和酮的缩合得到高度取代的吡啶。因此,仅通过三个步骤就可以通过简单的实验操作从市售试剂中合成不同取代的五芳基吡啶。
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更新日期:2020-01-17
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