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Diagnosis and management of neonatal diabetes mellitus: A survey of physicians' perceptions and practices in ASPED countries.
Diabetes Research and Clinical Practice ( IF 6.1 ) Pub Date : 2019-12-10 , DOI: 10.1016/j.diabres.2019.107975
Abdelhadi M Habeb 1 , Asma Deeb 2 , Nancy Elbarbary 3 , Salem A Beshyah 4
Affiliation  

AIM To ascertain the awareness and practice of neonatal diabetes mellitus (NDM) among paediatricians in Arab countries. METHODS An online questionnaire was distributed to physicians associated with the Arab Society for Paediatric Endocrinology and Diabetes (ASPED). RESULTS We received 126 replies, from 16 countries. All except one classified the survey's case scenario as NDM and 94% agreed that NDM patients should have detailed assessment to identify extra-pancreatic features. Although 92% felt that genetic testing is necessary, only 72% requesting them routinely and 32% unaware of the availability of free genetic testing. Insulin is considered the initial therapy for 93% and 80% diluted insulin to deliver accurate doses. Basal-bolus regimen was preferred by 36% and similar percentage used insulin pump. The remaining 28% favour long acting insulin alone. Oral sulfonylureas would be tried empirically by 34% and 69% would do so if genetic testing is unavailable. Whilst 70% have no local NDM management guidelines, 41% are unaware of any international guidelines. CONCLUSIONS The ASPED surveyed clinicians have good awareness of NDM diagnosis with marked variation in their practice raising the need to establish management guideline for the condition. The survey highlights areas to focus on in developing consensus and educational activities.

中文翻译:

新生儿糖尿病的诊断和管理:对ASPED国家医生的看法和实践的调查。

目的确定阿拉伯国家的儿科医生对新生儿糖尿病(NDM)的认识和实践。方法向与阿拉伯儿科内分泌和糖尿病学会(ASPED)相关的医师分发了在线问卷。结果我们收到了来自16个国家的126份答复。除了一个人以外,所有人都将调查的病例情况归类为NDM,94%的人同意NDM患者应进行详细评估以识别胰腺外特征。尽管92%的人认为必须进行基因检测,但只有72%的人例行要求进行基因检测,还有32%的人不知道免费的基因检测的可用性。胰岛素被认为是93%和80%稀释胰岛素提供准确剂量的初始疗法。36%的患者首选基础推注方案,使用胰岛素泵的比例相似。其余28%的人赞成单独使用长效胰岛素。如果无法进行基因检测,将有34%的经验性尝试口服磺脲类药物,而有69%的经验性尝试。尽管70%的人没有本地NDM管理指南,但41%的人不知道任何国际指南。结论ASPED接受调查的临床医生对NDM诊断有良好的认识,其实践中存在明显差异,因此需要建立针对该病的管理指南。该调查突出了在发展共识和教育活动中应重点关注的领域。结论ASPED接受调查的临床医生对NDM诊断有良好的认识,其实践中存在明显差异,因此需要建立针对该病的管理指南。该调查突出显示了在发展共识和教育活动中应重点关注的领域。结论ASPED接受调查的临床医生对NDM诊断有良好的认识,其实践中存在明显差异,因此需要建立针对该病的管理指南。该调查突出显示了在发展共识和教育活动中应重点关注的领域。
更新日期:2019-12-11
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