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Age-specific rate of undiagnosed diabetes and prediabetes in acute stroke.
Diabetes Research and Clinical Practice ( IF 6.1 ) Pub Date : 2019-12-09 , DOI: 10.1016/j.diabres.2019.107968
Paola Forti 1 , Fabiola Maioli 2 , Giorgia Arnone 2 , Valeria Nativio 2 , Marco Zoli 1 , Maura Coveri 2 , Giuseppe Di Pasquale 2 , Gaetano Procaccianti 3
Affiliation  

AIMS We investigated age-specific rates of undiagnosed diabetes and prediabetes among patients with acute stroke. METHODS We used data from 2223 patients with acute stroke consecutively admitted to an Italian Stroke Unit (SU) between 2010 and 2015. Information from medical records and glycated hemoglobin (HbA1c) measured on admission was retrospectively used to screen for diabetes and prediabetes defined according to standard criteria. RESULTS Overall rate of diabetes undiagnosed at admission and diabetes still undiagnosed at SU discharge were 9.7% and 6.7% but age-specific prevalence peaked up to 12.0% and 9.0% after age 80. At admission, the proportion of all undiagnosed diabetes on total diabetes cases was one out of every two cases before age 60 and three out of every four cases after age 80. In these same age intervals, one out of every three diabetes cases was still undiagnosed at SU discharge. Regardless of age, about three out of ten patients with acute stroke had prediabetes. Less than 2% of these patients had a prediabetes diagnosis before or after SU admission. CONCLUSIONS In patients with acute stroke, diabetes is substantially underdiagnosed before age 60 and after age 80. Prediabetes is highly prevalent but mostly undiagnosed at all ages.

中文翻译:

急性卒中中未诊断的糖尿病和糖尿病前期的按年龄分的比率。

目的我们调查了急性卒中患者中未确诊的糖尿病和前驱糖尿病的年龄特定比率。方法我们使用2010年至2015年连续入选意大利卒中病房(SU)的2223例急性中风患者的数据。回顾性地使用病历和入院时测得的糖化血红蛋白(HbA1c)资料筛查是否符合以下定义的糖尿病和前驱糖尿病:标准标准。结果入院时未确诊的糖尿病和SU出院时仍未确诊的糖尿病的总体发生率分别为9.7%和6.7%,但按年龄划分的患病率在80岁后达到最高,分别为12.0%和9.0%。入院时,所有未确诊的糖尿病占总糖尿病的比例在60岁之前,每2例中就有1例,在80岁之后,每4例中就有3例。在这些相同的年龄间隔中,在SU出院时,仍然有三分之二的糖尿病患者未被诊断。不论年龄大小,在急性卒中患者中,十分之三的患者患有前驱糖尿病。这些患者中只有不到2%的患者在SU入院之前或之后进行过糖尿病前诊断。结论在患有急性中风的患者中,糖尿病在60岁之前和80岁之后的诊断率明显不足。前驱糖尿病非常普遍,但在所有年龄段都未被诊断。
更新日期:2019-12-11
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