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Nature Chemical Biology ( IF 12.9 ) Pub Date : 2020-01-01 , DOI: 10.1038/s41589-019-0428-x
Michael A Erb 1
Affiliation  

Phenotypic screening is an engine of discovery for bioactive small molecules and can unravel novel mechanisms and pathways controlling cellular physiology. A recent study reveals the CPSF complex as a pharmacologically tractable target of JTE-607 and context-specific cancer dependency.

中文翻译:

处理销毁。

表型筛选是发现生物活性小分子的引擎,可以揭示控制细胞生理的新机制和途径。最近的一项研究表明,CPSF复合物是JTE-607和特定于上下文的癌症依赖性的药理学上可治疗的靶标。
更新日期:2019-12-11
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