Background

In 2010, sugar sweetened beverages (SSBs) were estimated to cause 12% of all diabetes, cardiovascular disease (CVD) and obesity-related cancer deaths in Mexico. Using new risk estimates for SSBs consumption, we aimed to update the fraction of Mexican mortality attributable to SSBs, and provide subnational estimates by region, age, and sex.

Methods

We used an established comparative risk assessment framework. All-cause mortality estimates were calculated from a recent pooled cohort analysis. Age- and sex-specific relative risks for SSBs-disease relationships were obtained from updated meta-analyses. Demographics and nationally representative estimates of SSBs intake were derived from the National Health and Nutrition Survey 2012; and mortality rates, from the National Institute of Statistics and Geography. Attributable mortality was calculated by estimating the population attributable fraction of each disease, with uncertainty in data inputs propagated through Monte Carlo probabilistic sensitivity analyses.

Results

In Mexican adults 20 years and older, 6.9% (95%UI: 5.4–8.5) of all cause-mortality was attributable to SSBs, representing 40,842 excess deaths/year (95%UI: 31,950–50,138). Furthermore, 19% of diabetes, CVD and obesity-related cancer mortality was attributable to SSBs (95%UI: 11.0–26.5), representing 37,000 excess deaths/year (95%UI 21,240–51,045). Of these, 35.6% were diabetes-related (95%UI 16.4–52.0). Proportional burden was highest in the South (22.8%), followed by the Center (18.0%) and North (17.4%). Men aged 45–64-years in the Center region had highest proportional mortality (37.2%), followed by 20–44-year-old men living in the South (35.7%) and both men and women aged 20–44 living in the Center (34.4%).

Conclusions

Utilizing current evidence linking SSBs to cardiometabolic disease and obesity-related cancers, earlier estimates of Mexican mortality attributable to SSBs could have been underestimated. Mexico urgently needs stronger policies to reduce SSBs consumption and reduce these burdens.

中文翻译：

---

墨西哥因含糖饮料消费导致的死亡率：最新情况。

 背景

2010 年，据估计，墨西哥 12% 的糖尿病、心血管疾病 (CVD) 和肥胖相关癌症死亡病例是由含糖饮料 (SSB) 造成的。我们利用新的 SSB 消费风险估计，更新了墨西哥因 SSB 导致的死亡率比例，并按地区、年龄和性别提供了次国家级估计。

 方法

我们使用了既定的比较风险评估框架。全因死亡率估计值是根据最近的汇总队列分析计算得出的。从更新的荟萃分析中获得了 SSB 与疾病关系的年龄和性别特异性相对风险。人口统计数据和全国代表性的 SSB 摄入量估计值来自 2012 年国家健康和营养调查；和死亡率，来自国家统计和地理研究所。通过估计每种疾病的人群归因分数来计算归因死亡率，并通过蒙特卡罗概率敏感性分析传播数据输入的不确定性。

 结果

在 20 岁及以上的墨西哥成年人中，6.9%（95%UI：5.4–8.5）的所有原因死亡率可归因于 SSB，即每年超额死亡 40,842 人（95%UI：31,950–50,138）。此外，19% 的糖尿病、CVD 和肥胖相关癌症死亡率可归因于 SSB（95%UI：11.0–26.5），相当于每年超额死亡 37,000 例（95%UI 21,240–51,045）。其中，35.6% 与糖尿病相关（95%UI 16.4–52.0）。南部地区的负担比例最高（22.8%），其次是中部（18.0%）和北部（17.4%）。中部地区 45-64 岁的男性死亡率最高（37.2%），其次是南部地区 20-44 岁的男性（35.7%），以及南部地区 20-44 岁的男性和女性。中心（34.4%）。

 结论

利用目前将 SSB 与心脏代谢疾病和肥胖相关癌症联系起来的证据，早期对墨西哥因 SSB 造成的死亡率的估计可能被低估了。墨西哥迫切需要采取更强有力的政策来减少SSB的消费并减轻这些负担。