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New Drugs for an Old Foe: Mycobacterium tuberculosis Meets PSC-Derived Macrophages.
Stem Cell Reports ( IF 5.9 ) Pub Date : 2019-12-10 , DOI: 10.1016/j.stemcr.2019.11.006
Kathrin Haake 1 , Nico Lachmann 1
Affiliation  

Infections with Mycobacterium tuberculosis (Mtb) are still among the top 10 causes of death worldwide, highlighting the utmost need for new forms of medical treatments. In this issue of Stem Cell Reports, Han et al. (2019) describe a technique to screen therapeutically active compounds targeting Mtb using pluripotent stem cell-derived macrophages.



中文翻译:

对抗老敌人的新药:结核分枝杆菌遇到了PSC衍生的巨噬细胞。

结核分枝杆菌Mtb)感染仍是全球十大死亡原因之一,这突出表明了对新形式医学治疗的最高需求。在本期《干细胞报告》中,Han等人。(2019)描述了一种使用多能干细胞衍生的巨噬细胞筛选针对Mtb的治疗活性化合物的技术。

更新日期:2019-12-10
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