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The power of one: advances in single-cell genomics in the kidney.
Nature Reviews Nephrology ( IF 28.6 ) Pub Date : 2020-02-01 , DOI: 10.1038/s41581-019-0237-1
Abbe R Clark 1, 2 , Anna Greka 1, 2
Affiliation  

Single-cell genomics provide a powerful approach to investigate the intrinsic complexity of the kidney and understand the diverse cell types and states that exist during kidney development, homeostasis and disease. Several advances were made in 2019 that enhance our understanding of kidney immune cell states in health and disease and the quality of current kidney organoid model systems for studying human diseases.

中文翻译:

一个的力量:肾脏单细胞基因组学的进展。

单细胞基因组学提供了一种强大的方法来研究肾脏的内在复杂性,并了解肾脏发育、体内平衡和疾病过程中存在的不同细胞类型和状态。2019 年取得了几项进展,增强了我们对健康和疾病中肾脏免疫细胞状态的理解,以及当前用于研究人类疾病的肾脏类器官模型系统的质量。
更新日期:2019-12-09
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