The present study evaluated the safety of dietary administration of the microalga Scenedesmus obliquus at high doses, the influence on blood biochemical profile, and in vivo protein quality in male Wistar rats. The microalga exhibited a high amount of fibers, carotenoids, phenolic compounds, linolenic and linoleic acid, and great antioxidant activity. The diet containing Scenedesmus obliquus was well tolerated, with good protein digestibility and maintenance of growth and weight of the animals. The intake of the microalga reduced triglycerides of up to 70%, atherogenic index of up to 80%, and serum glucose of up to 42% concentrations as compared with the standard diet. No alterations were observed in the analyzed organs by histology, suggesting that the microalga Scenedesmus obliquus can be used as potential safe food and may represent a sustainable source of food.

本研究评估了雄性Wistar大鼠高剂量微藻斜饮食的饮食管理安全性，对血液生化特性的影响以及体内蛋白质质量。微藻表现出大量的纤维，类胡萝卜素，酚类化合物，亚麻酸和亚油酸，并具有很高的抗氧化活性。含有斜角藻的饮食良好的耐受性，具有良好的蛋白质消化率，并能维持动物的生长和体重。与标准饮食相比，摄入微藻减少的甘油三酸酯高达70％，动脉粥样硬化指数高达80％，血清葡萄糖的浓度高达42％。在组织学上未观察到变化，这表明微藻斜角藻可以用作潜在的安全食品，并且可以代表可持续的食品来源。