Superparamagnetic nanoparticles for biomedical applications.,Journal of Materials Chemistry B

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Superparamagnetic nanoparticles for biomedical applications.
Journal of Materials Chemistry B ( IF 6.1 ) Pub Date : 2019-12-23 , DOI: 10.1039/c9tb01955c
Yufen Xiao ₁ , Jianzhong Du

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In this review, we summarized recent advances in the development and biological applications of polymeric nanoparticles embedded with superparamagnetic iron oxide nanoparticles (SPIONs). Superparamagnetic polymeric nanoparticles include core-shell nanoparticles, superparamagnetic polymeric micelles and superparamagnetic polymersomes. They have potential for various biomedical applications, including magnetic resonance imaging (MRI) contrast agents, drug delivery, detection of bacteria, viruses and proteins, etc. Finally, the challenges in the design and preparation of superparamagnetic nanoparticles towards clinical applications are explored and the prospects in this field are proposed.

中文翻译：

用于生物医学的超顺磁性纳米粒子。

在这篇综述中，我们总结了嵌入超顺磁性氧化铁纳米粒子（SPIONs）的聚合物纳米粒子的开发和生物学应用的最新进展。超顺磁性聚合物纳米颗粒包括核-壳纳米颗粒，超顺磁性聚合物胶束和超顺磁性聚合物小体。它们在各种生物医学应用中具有潜力，包括磁共振成像（MRI）造影剂，药物输送，细菌，病毒和蛋白质的检测等。提出了该领域的前景。

更新日期：2019-12-23

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