Abstract A nature-friendly method was developed to synthesize novel Mn-Ag co-doped FeO nanoparticles using Solanum Trilobatum leaf extract. Crystallinity nature, size, morphology and chemical composition were analysed from high resolution characterisation techniques such as XRD-XPS, FESEM-EDS, SEM-TEM, ICP-CHNS, UV–visible, FTIR, FT-Raman and Zeta potential. X-ray diffraction evident the cubic phase of the nanoparticles, FESEM images gives the glimpse of agglomerated nano-spherical shaped FeO particles and ICP measures the Fe content in the samples. Mn-Ag co-doped FeO nanoparticles showed a convincing result for antibacterial activity and also acted as a powerful factor in MTT assay performed against MCF-7 cells compared to HeLa cells and also it doesn’t show high effectivity against Vero cells. Hence, this Mn-Ag Co-doped FeO nanoparticles can bring a modulation in anticancer drug delivery system.

中文翻译：

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Mn-Ag 共掺杂 Fe3O (Fe1-2xMnxAgx) 纳米颗粒的生物合成：作为一种有效的消毒剂和抗癌剂

摘要 开发了一种使用三叶茄叶提取物合成新型 Mn-Ag 共掺杂 Fe3O 纳米颗粒的自然友好方法。结晶度性质、尺寸、形态和化学成分通过高分辨率表征技术进行分析，例如 XRD-XPS、FESEM-EDS、SEM-TEM、ICP-CHNS、UV-visible、FTIR、FT-Raman 和 Zeta 电位。X 射线衍射表明纳米颗粒的立方相，FESEM 图像给出了团聚纳米球形 FeO 颗粒的一瞥，ICP 测量样品中的 Fe 含量。与 HeLa 细胞相比，Mn-Ag 共掺杂的 Fe3O 纳米颗粒显示出令人信服的抗菌活性结果，并且在对 MCF-7 细胞进行的 MTT 测定中也起到了强大的作用，而且它对 Vero 细胞也没有表现出高效率。因此，